
Cartoning Machine
A GMP-compliant cartoning system offering ±0.5mm positioning accuracy, 99.99% pass rate, strong adhesion, and full traceability—ideal for high-precision packaging of diverse liquid formulations.
This advanced cartoning system is designed to meet the stringent demands of pharmaceutical and biotech industries by ensuring high precision, strong adhesion, and full traceability for packaging various types of liquid formulations. It achieves a positioning accuracy of ±0.5mm with bottle/bag insertion deviation ≤±1mm, eliminating issues like jamming, missing, or incorrect loading, thus achieving a 99.99% pass rate.
The system ensures excellent paper box forming precision with neatly folded edges (deviation ≤±0.3mm) and robust bonding, providing a peel strength ≥5N/25mm, which guarantees no glue failure or deformation, meeting transportation packaging standards. The accuracy rate for inserting instructions is 100%, supporting automatic folding and precise placement of single-page/multi-page instructions without omission, inversion, or creasing, suitable for different instruction sizes.
The system’s design includes flexible conveying and cushioned positioning, preventing product damage (breakage rate ≤0.005%) and ensuring the integrity of liquid formulation packaging. Various sealing methods such as hot melt adhesive, pressure-sensitive adhesive, and tuck-in flaps are supported, ensuring flat seals without excess glue, making it resistant to drops and vibrations, ideal for long-distance transportation.
Supporting mixed packaging of multiple specifications (e.g., 1 bottle + 1 instruction + 1 gift), the system maintains a material ratio accuracy of 100%, avoiding underloading or overloading. Excellent repeatability within batches ensures consistent product appearance. Precise detection of unopened or partially opened boxes allows for automatic rejection, enhancing subsequent cartoning efficiency.
Fully compliant with GMP, FDA 21 CFR Part 11, EU GMP Annex 11, the system includes tamper-proof electronic batch records (EBR) storing parameters like speed, pass rate, box batches, and operator data. IQ/OQ/PQ validation packages and material compatibility reports facilitate rapid GMP certification. Full traceability through barcode/QR code linking bottle/bag batches, box batches, instruction batches, and cartoning parameters ensures tracking from production to end-user.
Designed for flexibility, the system supports various types of liquid formulation containers and box sizes, including rectangular, square, and custom-shaped boxes, accommodating 1-50 bottles/bags per box. With a capacity range of 30-300 boxes/min, it supports small-scale trials, pilot runs, and large-scale production, enabling quick changeovers (≤20 minutes). Modular design allows seamless integration with labeling machines, palletizers, and inspection equipment, facilitating an “all-in-one” automated process from labeling to cartoning and palletizing.
Operated via PLC + touchscreen controls, it offers 100+ programmable cartoning recipes, real-time monitoring, and self-diagnosis features, facilitating remote management and rapid fault resolution. Energy-saving technologies ensure low maintenance costs and long service life with international components, while also reducing waste and improving efficiency.
| Category | Specification / Feature |
|---|---|
| Cartoning Positioning Accuracy | ±0.5 mm; bottle/bag insertion deviation ≤±1 mm |
| Box Forming Precision | Neatly folded edges (deviation ≤±0.3 mm); peel strength ≥5N/25mm |
| Instruction Insertion Accuracy | 100%; supports single/multi-page folding and insertion |
| Product Damage Rate | ≤0.005%; flexible conveying and cushioned positioning |
| Sealing Methods | Hot melt adhesive, pressure-sensitive adhesive, tuck-in flaps |
| Mixed Packaging Support | Supports 1 bottle + 1 instruction + 1 gift; material ratio accuracy 100% |
| Batch Consistency | Parameter deviation ≤±0.5% |
| Regulatory Compliance | GMP, FDA 21 CFR Part 11, EU GMP Annex 11 |
| Data Integrity | Tamper-proof EBR; logs speed, pass rate, box batches, operator data |
| Validation Documentation | Full IQ/OQ/PQ, cartoning process validation report, material compatibility report |
| Material Compatibility | 316L SS, food-grade plastics; meets USP Class VI |
| Cleanroom Classification | Supports CIP online cleaning |
| Traceability | Barcode/QR links bottle/bag batches, box batches, instruction batches, cartoning params |
| Certifications | CE, ISO 9001, FDA registered |
| Capacity Range | 30–300 boxes/min |
| Integrated Modules | Automatic feeding, product sorting, instruction insertion, anti-counterfeiting label application, coding |
| Changeover Time | ≤20 minutes |
| Special Functions | Flexible sealing options |
| Modular Design | Scalable modules for seamless integration |
| Automation Level | Fully automatic feeding → forming → loading → insertion → sealing → inspection |
| Control System | PLC + color touchscreen; manual/auto modes |
| Remote Operation | Real-time monitoring via PC/mobile; multi-language support |
| Fault Diagnosis | Auto-detect missing boxes, products, instructions, insufficient glue |
| Safety Features | Overload protection, anti-pinch protection, emergency stop, door interlock |
| Maintenance | Low-maintenance international components; detailed manuals & video tutorials |